TCT-417 REALISE Trial: Renal Denervation by Ultrasound Transcatheter Emission: Six Month Results

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منابع مشابه

Renal denervation in patients with resistant hypertension: six-month results.

INTRODUCTION Increased activation of the sympathetic nervous system plays a central role in the pathophysiology of hypertension (HTN). Catheter-based renal denervation (RDN) was recently developed for the treatment of resistant HTN. AIM To assess the safety and efficacy of RDN for blood pressure (BP) reduction at six months in patients with resistant HTN. METHODS In this prospective registr...

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Expanded indications for transcatheter renal denervation

Renal denervation (RDN) is a catheter-based procedure introduced in 2009 as a treatment of resistant hypertension. The method is based on the concept that resistant hypertension is a result of hyperactivity of the sympathetic nervous system (SNS), and therefore reducing the impact of the SNS by ablating the renal nerves should eliminate the condition. Since 2009 numerous investigators have prov...

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AIMS Renal denervation using the point-by-point application of radiofrequency energy delivered by the first-generation Symplicity system is effective in lowering office blood pressure but may be time-consuming. The OneShot Renal Denervation System with a balloon-mounted spiral electrode potentially shortens and simplifies the procedure. This study is a hypothesis-generating first-in-human study...

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Randomized comparison of renal denervation versus intensified pharmacotherapy including spironolactone in true-resistant hypertension: six-month results from the Prague-15 study.

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Resistant hypertension and renal denervation. Considerations on the results of the SYMPLICITY HTN-3 trial.

Resistant hypertension is undoubtedly a real clinical challenge, given that it increases cardiovascular events and has no effective treatment. Thus, it is easy to see why renal sympathetic denervation (RDN) has raised expectations among physicians treating patients with this serious disease. The SYMPLICITY HTN-1 trial was a proof-of-principle trial followed by the SYMPLICITY HTN-2 trial, which ...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2014

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2014.07.466